Chloroquine is an anti-malarial medication that is a part of the aminoquinoline family. The main component of Chloroquine is chloroquine phosphate. The treatment is distributed as tablets and is available in quantities of 250mg and 500mg.
How it works
Chloroquine targets parasites that are known as Plasmodium. Plasmodium enter red blood cells in the body and then multiply belong causing the cells to burst open and spread further throughout the body. Plasmodium digest the hemoglobin in the red blood cells which causes this substance to divide into haem and globin. Haem is toxic to the Plasmodium so the Plasmodium converts it to a more harmful substance. The Chloroquine works by preventing this transformation, thus allowing the haem to destroy the Plasmodium.
Chloroquine can be used to both prevent malaria within a person as well as treat it in an infected individual. It can also help to overcome a parasitic infection known as extraintestinal amebiasis.
It is imperative that you see a clinician before beginning a treatment plan that includes Chloroquine. You should only take the amount of Chloroquine that has been deemed appropriate by a medical expert. It is unwise to either increase or decrease this amount without prior consultation with your clinician. Doing so could have negative consequences for you.
If you are using Chloroquine as a preventative measure, it is best to do so about two weeks before you may be exposed to the parasite. If you are unable to do this, you may require a higher loading dose to get started. You should inform your clinician about your impending schedule so that he or she may decide what the amount needs to be.
Even if you are not infected, you will need to continue treatment for eight weeks after the threat is no longer imminent.
For the prevention of malaria as well as the treatment of malaria, the dose is calculated depending on the weight of the individual.
For preventative treatment, however, the dose for a child should never exceed that of an adult, regardless of what their weight may be.
With the continuous use of Chloroquine, you may begin to notice some unusual occurrences. These may include:
Changes to hair color
A loss in volume of hair
Increased sensitivity to the sun
Discoloration or redness of the skin
Bleeding from the gums
Peeling of the skin
Presence of blood in either urine or stools
If you observe any of these issues or other medical concerns, make sure to contact a medical expert as soon as possible.
You should not take Chloroquine in the following instances:
If you have a hypersensitivity to one or more of the ingredients in Chloroquine
If you have vision issues, particularly retinal changes
If you are currently taking arsenic, cimetidine, astemizole, terfenadine, cisapride, dofetilide, and quinacrine
It is vital that you tell your clinician of all of the medications that have been prescribed. This is because taking them with Chloroquine may decrease their effectiveness or increase the possibility of an adverse reaction.
Children and elderly individuals may have a greater sensitivity to Chloroquine than other people.
Inform a medical expert of these particular conditions:
Blood diseases including porphyria
Conditions that cause seizures
A glucose-6-phosphate dehydrogenase (G-6-PD) deficiency
Problems with the digestive or central nervous system
Issues with your liver
If you are pregnant, you need to ask a clinician whether or not it is safe for you to take Chloroquine. Chloroquine can be passed through breast milk and should be used by nursing mothers.