Sinequan is a brand name for doxepin, an antidepressant and a nerve pain medication.
How It Works
Sinequan, also known by its generic name doxepin, is a tricyclic antidepressant. They are called so because of the ring-shape of the chemical compounds. Sinequan works by blocking reuptake of the neurotransmitters serotonin and norepinephrine by the nerve cells of the brain. This action makes these neurotransmitters more available for use by other brain cells. Clinical studies have shown that more availability of serotonin and norepinephrine can lead to effects such as elevation of mood and improvements of symptoms of depression.
Sinequan is available as oral and topical medications. It’s most commonly available in oral form and is used to treat a number of medical conditions. Sinequan is approved by the FDA to treat depression. It may also be prescribed to treat anxiety disorders, insomnia and certain sleeping problems. It may also be prescribed to treat itchiness and chronic idiopathic urticaria (hives). Topical Sinequan is used to treat atopic dermatitis and lichen simplex chronicus. In some countries, like Australia and the UK, Sinequan is only approved for use for major depression and eczema.
Dosage of Sinequan will vary depending on your unique medical situation. Your doctor will prescribe you the correct dose of Sinequan, which you must follow exactly.
Read the patient information leaflet provided with the packaging before use. Sinequan oral and topical medications must be used differently.
Oral Sinequan is prescribed to be taken 1 to 3 times daily usually. Sinequan may cause sleepiness. If you only have to take one dose of Sinequan per day, it’s recommended to take this dose close to bedtime to prevent daytime drowsiness.
The oral liquid suspension of Sinequan comes with a dropper. Use only this dropper to measure the exact prescribed dose. Do not use household spoons or other types of droppers to measure doses.
You can mix liquid Sinequan with water, milk, or orange juice to make swallowing easy. Do not mix Sinequan liquid suspension with soda or other carbonated drinks. Drink the Sinequan juice mixture right away. Do not make extra batches for future use.
Sinequan may cause one or more of the following side effects:
Ringing in ears
Breast swelling (in both men and women)
Decreased sex drive
Call your doctor if the side effects persist or gets worse with time.
Do not take Sinequan if you are allergic to any of the ingredients in the drug.
Certain preexisting medical conditions make Sinequan unsafe to consume. Ask your doctor if Sinequan is safe to use given your medical history.
Do not take Sinequan when pregnant, breastfeeding or about to get pregnant without consulting a doctor first.
Tell the physician any other medication, over-the-counter drugs, herbal supplements or vitamins you may be taking as a precaution against adverse drug interactions.
You may not feel effects of Sinequan right away. You must take this medication regularly to benefit from the effects.
Never take Sinequan in higher doses than prescribed. High doses of this drug can lead to toxic overdoses. Immediately contact a Poison Control Center if you suspect that you may have overdosed on Sinequan.